An interesting article today by Bruce Cohen on the use of “next-generation” molecular light generators can be found here. These inorganic atoms, which are typically doped with some other material, are designed to have desirable excitation properties. For example, their use minimizes the amount of deleterious photobleachingin the sample. On the other hand, they are often large, making them difficult to use biologically without altering the system under study. However, as their size decreases, these molecules will likely play a large role in neuroscience in the coming years.